International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
Barnes, Nicholas M.; Ahern, Gerard P.; Becamel, Carine; Bockaert, Joel; Camilleri, Michael; Chaumont-Dubel, Severine; Claeysen, Sylvie; Cunningham, Kathryn A.; Fone, Kevin C.; Gershon, Michael; Di Giovanni, Giuseppe; Goodfellow, Nathalie M.; Halberstadt, Adam L.; Hartley, Rachel M.; Hassaine, Gherici; Herrick-Davis, Katharine; Hovius, Ruud; Lacivita, Enza; Lambe, Evelyn K.; Leopoldo, Marcello; Levy, Finn Olav; Lummis, Sarah C. R.; Marin, Philippe; Maroteaux, Luc; McCreary, Andrew C.; Nelson, David L.; Neumaier, John F.; Newman-Tancredi, Adrian; Nury, Hugues; Roberts, Alexander; Roth, Bryan L.; Roumier, Anne; Sanger, Gareth J.; Teitler, Milt; Sharp, Trevor; Villalon, Carlos M.; Vogel, Horst; Watts, Stephanie W.; Hoyer, Daniel
2021
Résumé
5 HT receptors expressed throughout the human body are targets for established therapeutics and various drugs in development. Their diversity of structure and function reflects the important role 5-HT receptors play in physiologic and pathophysiological processes. The present review offers a framework for the official receptor nomenclature and a detailed understanding of each of the 14 5-HT receptor subtypes, their roles in the systems of the body, and, where appropriate, the (potential) utility of therapeutics targeting these receptors.
Significance Statement-This review provides a comprehensive account of the classification and function of 5-hydroxytryptamine receptors, including how they are targeted for therapeutic benefit.
Significance Statement-This review provides a comprehensive account of the classification and function of 5-hydroxytryptamine receptors, including how they are targeted for therapeutic benefit.
Détails
Titre
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
Auteur(s)
Barnes, Nicholas M. ; Ahern, Gerard P. ; Becamel, Carine ; Bockaert, Joel ; Camilleri, Michael ; Chaumont-Dubel, Severine ; Claeysen, Sylvie ; Cunningham, Kathryn A. ; Fone, Kevin C. ; Gershon, Michael ; Di Giovanni, Giuseppe ; Goodfellow, Nathalie M. ; Halberstadt, Adam L. ; Hartley, Rachel M. ; Hassaine, Gherici ; Herrick-Davis, Katharine ; Hovius, Ruud ; Lacivita, Enza ; Lambe, Evelyn K. ; Leopoldo, Marcello ; Levy, Finn Olav ; Lummis, Sarah C. R. ; Marin, Philippe ; Maroteaux, Luc ; McCreary, Andrew C. ; Nelson, David L. ; Neumaier, John F. ; Newman-Tancredi, Adrian ; Nury, Hugues ; Roberts, Alexander ; Roth, Bryan L. ; Roumier, Anne ; Sanger, Gareth J. ; Teitler, Milt ; Sharp, Trevor ; Villalon, Carlos M. ; Vogel, Horst ; Watts, Stephanie W. ; Hoyer, Daniel
Publié dans
Pharmacological Reviews
Volume
73
Numéro
1
Pages
310-520
Date
2021-01-01
Editeur
Bethesda, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
ISSN
0031-6997
1521-0081
1521-0081
Mots-clés (libres)
Autres identifiant(s)
Afficher la publication dans Web of Science
Laboratoires
LCPPM
Le document apparaît dans
Production scientifique et compétences > SB - Faculté des sciences de base > SB Archives > LCPPM - Laboratoire de chimie physique des polymères et membranes
Publications validées par des pairs
Travail produit à l'EPFL
Publié
Reviews
Publications validées par des pairs
Travail produit à l'EPFL
Publié
Reviews
Date de création de la notice
2021-03-26